Center for
Molecular and Regenerative Medicine
The Center for Molecular and Regenerative Medicine is to create a comprehensive infrastructure for musculoskeletal
research that facilitates translation of research in the laboratory into
breakthroughs in patient care at The University of Chicago Medical Center. As such, the mission of this organization is to
improve our ability to treat musculoskeletal problems through investigation of
key mechanisms underlying orthopaedic diseases, screening of novel interventions
through translational models and testing promising new approaches in clinical
trials.
Musculoskeletal disorders encompass a broad range of
diseases, from traumatic injuries to degenerative conditions to cancer, each
potentially involving different components of the mesenchyme, such as bone,
cartilage, tendon, muscle, etc. To match the range of pathologies present, the
Center for Molecular and Regenerative Medicine has been organized around key
modules that focus on tissue- and/or disease-specific areas, each of which
reflect the most common clinical problems that we treat as orthopaedic surgeons.
Each module is composed of a team of investigators, including basic scientists,
clinician-scientists as well as clinicians, in an effort to supply the full
complement of researchers necessary to conduct “bench-to-bedside” research in
each area. Thus, in addition to their clinical and educational commitments at
The University of Chicago, our faculty is actively involved in a broad range of
research on bone and musculoskeletal diseases, which have been highlighted in
the following areas.
Research Programs
Geraldine Mary Maley Research
Award
Suzanne Berman
Memorial Lectureship
Gerald S. Laros Memorial
Lectureship
Recent Publications
The Center Seminars
-
2009: Shu
Chien, MD, PhD. The University
Professor, Y.C. Fung Professor of Bioengineering and Medicine at University
of California, San Diego. Dr. Chien is one of the nine individuals who are a
member of all three U.S. National Academies (National Academy of Sciences,
National Academy of Engineering, and Institute of Medicine), as well as the
American Academy of Arts and Sciences. He is a Member of Academia Sinica in
Taiwan and a Foreign Member of the Chinese Academy of Sciences in Beijing. "Mechanotransduction
in endothelial cells: Importance of stress direction". (Co-sponsored by
Department of Surgery).
-
2008:
Karen Lyons, PhD. Professor, Department of
Molecular, Cell and Developmental Biology, and Department of Orthopaedic
Surgery, University of California Los Angeles, CA. "BMP
Signaling in the Growth Plate". (Co-sponsored by
Committee on Genetics).
-
2008:
Donald G. Phinney, PhD, Professor and
Associate Director for Research, Center for Gene Therapy, Tulane University,
New Orleans, LA. "A Sage View of Mesenchymal Stem Cells".
-
2008:
Di Chen, MD, PhD, Associate Professor,
Center for Musculoskeletal Research and Department of Orthopaedics,
University of Rochester Medical Center, Rochester, NY. "The Role of
Canonical Wnt Signaling in Bone and Joint Remodeling".
-
2007:
Gerard Karsenty, MD. PhD., Professor and Chairman, Department of
Genetics & Development, Columbia University, New York, NY. "Molecular
Genetic Analysis of Skeletal Biology". (Co-sponsored by
Committee on Genetics).
-
2007:
Linheng Li, PhD,
Associate Investigator, The Stowers Institute for Medical Research, Kansas
CIty, MO. "Stem cells and stem cell niches".
(Co-sponsored by Committee on Molecular Committee).
-
2006:
Yejia Zhang, MD, PhD, Assistant Professor of
Physical Medicine & Rehabilitation, Thomas Jefferson University Hospital,
Philadelphia, PA. "Cartilage Biology and Degenerative Intervertebral Disc
Repair".
-
2006:
A Hari
Reddi, PhD, Lawrence Ellison Chair Professor in Musculoskeletal
Molecular Biology and Director of
Center for Tissue Regeneration
and Repair at the University of California Medical
Center, Davis, CA. "Regeneration of Bone and Cartilage: Role
of Morphogenetic Proteins".
Last update:
January 10, 2010 |
